2011-2013

Teng BL, Hacker KE, Chen S, Means AR, Rathmell WK. (2011) Tumor suppressive activity of prolyl isomerase Pin1 in renal cell carcinoma. Mol Oncol. Oct;5(5):465-74. doi: 10.1016/j.molonc.2011.06.002. Epub 2011 Jun 28.

Brannon AR, Haake SM, Hacker KE, Pruthi RS, Wallen EM, Nielsen ME, Rathmell WK. Eur Urol. 2012 Meta-analysis of clear cell renal cell carcinoma gene expression defines a variant subgroup and identifies gender influences on tumor biology. Feb;61(2):258-68. doi: 10.1016/j.eururo.2011.10.007. Epub 2011 Oct 18. PMID:22030119

Neel NF, Rossman KL, Martin TD, Hayes TK, Yeh JJ, and Der CJ. TheRalB small GTPase mediates invadopodia formation through a GTPase activating protein-independent function of the RalBP1/RLIP76 effector. 2012 Apr;32(8):1374-86. doi: 10.1128/MCB.06291-11. Epub 2012 Feb 13. PMCID: PMC3318593.

Cook DR, Solski PA, Bultman SJ, Kauselmann G, Schoor M, Kuehn R, Friedman LS, Cowley DO, Van Dyke T, Yeh JJ, Johnson L, Der CJ. (2011) The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration. Genes Cancer. 2(10):932-42. PMCID: PMC3374631

Neel NF, Martin TD, Stratford JK, Zand TP, Reiner DJ, Der CJ. (2011). The RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery. Genes Cancer. 2011 Mar;2(3):275-87. doi: 10.1177/1947601911407329. PMID: 21779498

Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T, Feuerlein S, Syn WK, Jung Y, Witek RP, Choi S, Michelotti GA, Rangwala F, Merkle E, Lascola C, Diehl AM. (2011) Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. PLoS One. 2011;6(9):e23943. Epub 2011 Sep 2. PMCID: PMC3166282

Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T, Feuerlein S, Syn WK, Jung Y, Witek RP, Choi S, Michelotti GA, Rangwala F, Merkle E, Lascola C, Diehl AM. (2011) Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. PLoS One. 2011;6(9):e23943. Epub 2011 Sep 2. PMCID: PMC3166282

Chan IS, Ginsburg GS. (2011) Personalized medicine: progress and promise. Annu. Rev. Genomics Hum. Genet. 2011 Sep 22;12:217-44. Xie G, Choi SS, Syn WK, Michelotti GA, Swiderska M, Karaca G, Chan IS, Chen Y, Diehl AM. (2012) Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation. Gut. 2012 Feb 23. [Epub ahead of print]

Chen Y, Choi SS, Michelotti GA, Chan IS, Swiderska M, Karaca GF, Xie G, Moylan CA, Garibaldi F, Premont R, Suliman HB, Piantodosi CA, Diehl AM. (2012) Hedgehog controls hepatic stellate cell fate by regulating metabolism. Gastroenterology. 2012 Aug 8. [Epub ahead of print]

Chen Y, Choi SS, Michelotti GA, Chan IS, Swiderska M, Karaca GF, Xie G, Moylan CA, Garibaldi F, Premont R, Suliman HB, Piantodosi CA, Diehl AM. (2012) Hedgehog controls hepatic stellate cell fate by regulating metabolism. Gastroenterology. In press.

Pereira TA, Xie G, Choi SS, Syn WK, Voieta, I, Lu J, Chan IS, Swiderska M, Amaral KB, Antunes CM, Secor WE, Witek RP, Lambertucci JR, Pereira FL, Diehl AM. Macrophage-derived Hedgehog Ligands Promotes Fibrogenic and Angiogenic Responses in Human Schistosomiasis mansoni. Liver International. (Accepted August 2, 2012)

Chan IS, Guy CD, Chen Y, Lu J, Swiderska M, Michelotti GA, Karaca GF, Xie G, Kruger L, Syn WK, Anderson BR, Pereira TA, Choi SS, Baldwin AS, Diehl AM. Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma. (Under Review, Cancer Research)

*Duncan JS, *Whittle MC, Nakamura K, Abell AN, Midland AA, Zawistowski JS, Johnson NL, Granger DA, Vincent Jordan N, Darr DB, Usary J, Kuan PF, Smalley DM, Major B, He X, Hoadley K, Zhou B, Sharpless NE, Perou CM, Kim WY, Gomez SH, Chen X, Jin J, Frye SV, Earp HS, Graves LM, Johnson, GL. (2012) Dynamic reprogramming of the Kinome in response to targeted MEK inhibition in Triple Negative Breast Cancer. Cell. 149:307-21. PMCID: PMC3328787 *equal contribution, co-first-authors

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