2005-2010

Simin, K, Hill, R, Song, Y, Zhang, Q, Bash, R, Cardiff, RD, Yin, C, Xiao, A, McCarthy, K, and Van Dyke, T. (2005). Deciphering cancer complexities in genetically engineered mice. Cold Spring Harb Symp Quant Biol. 70:283-90.

Chai, J, Charboneau, A, Betz, BL. and Weissman, BE. (2005). Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid cells. Cancer Res. 65:10192-10198.

Berzat, AC, Brady, DC, Fiordalisi, JJ. and Cox, AD. (2005). Using inhibitors of prenylation to block localization and transforming activity. Methods Enzymol. 407: 575-597.

Hahn, AM, Huye, LE, Ning, S, Webster-Cyriaque, J. and Pagano, JS. (2005). Interferon regulatory factor 7 is negatively regulated by the Epstein-Barr virus immediate-early gene, BZLF-1. J Virol. 79: 10040-10052.

Hutsell, SQ. and Sancar, A. (2005). Nucleotide excision repair, oxidative damage, DNA sequence polymorphisms, and cancer treatment. Clin Cancer Res. 11: 1355-1357.

Keller, PJ, Gable, CM, Wing, MR. and Cox, AD. (2005). Rac3-mediated transformation requires multiple effector pathways. Cancer Res. 65: 9883-90.

Fiordalisi, JJ, Keller, PJ. and Cox, AD. (2005). PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility. Cancer Res. 66: 3153-3161.

Keller, PJ, Fiordalisi, JJ, Berzat, AC. and Cox, AD. (2005). Visual monitoring of post-translational lipid modifications using EGFP-GTPase probes in live cells. Methods. 37: 131-137.

Morrison, JA. and Raab-Traub, N. (2005). Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of {beta}-catenin signaling. J Virol. 79: 2375-2382.

Baines, AT, Lim, KH, Shields, JM, Campbell, PM, Lambert, JM, Counter, CM, Der, CJ, and Cox, AD. (2005). Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and Ras effector expression to Human Tumor Cell Growth. Methods Enzymol, 407, 556-574.

Unsal-Kacmaz, K, Mullen, TE, Kaufmann, WK. and Sancar, A. (2005) Timeless connects the human circadian clock and cell cycle checkpoints. Mol Cell Biol. 25: 3109-16.

Zhous T, Chou J, Simpon DA, Zhou Y, Mullen TE, Medeiros M, Bushel PR, Paules RS, Yang X, Hurban P, Lobenhofer EK, Kaufmann WK. (2005) Profiles of global gene expression in ionizing radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence.

Zhou T*, Chou J*, Mullen TE*, Zhou Y, Simpson DA, Li L, Bushel PR, Paules RS, Kaufmann WK. (2005) A method to distinguish active trans-repression of genotoxin-induced cellular injury from passive synchronization behind cell cycle checkpoints. (*contributed equally).

Rossman, KL, Der, CJ and Sondek, J. (2005). Abstract GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol. 2: 167-80.

Wennerberg, K, Rossman, KL, and Der, CJ. (2005). The Ras superfamily at a glance. J Cell Sci. 118: 843-846. Mitin, N.Y, Rossman, K.L. and Der, C.J. (2005). Signaling interplay in Ras superfamily function. Curr Biol. 15 :R563-574.

Wang, L, Dittmer, DP, Tomlinson, CC, Fakharim, FD. and Damania, B. (2006). Immortalization of primary endothelial cells by the K1 protein of Kaposi’s sarcoma-associated herpesvirus. Cancer Res. 66: 3658-3666.

Yohe, ME, Rossman, KL, Gardner, O.S, Karnoub, AE, Snyder, JT, Gershburg, S, Graves, LM, Der, CJ, and Sondek, J. (2007). Auto-inhibition of the Dbl-family protein Tim by an N-terminal helical motif. J Biol Chem. 2007 Mar 2; [Epub ahead of print].

Booden, MA, Ulku, AS, and Der, CJ. (2005). Cellular assays of oncogene transformation. In Cell Biology: A Laboratory Handbook, Volume 1.

Brannon, AR, Maresca, JA, Boeke, JD, Basrai, MA, and McBride, AA. (2005). Reconstitution of papillomavirus E2-mediated plasmid maintenance in Saccharomyces cerevisiae by the Brd4 bromodomain protein. J. Celis, N, Carter, K, Simons, V, Small, and T Hunter, editors. Third Edition. Academic Press, San Diego, CA. Proc Natl Acad Sci USA. 102: 2998-3003. PMID:15710895

Yang, Y, Goldstein, BG, Chao, HH. and Katz, JP. (2005). KLF4 and KLF5 Regulate Proliferation, Apoptosis, and Invasion in Esophageal Cancer Cells. Cancer Biology and Therapy. 4: 1216-1221.

Clifford, DM, Stark, KE, Gardner, KE, Hoffman-Benning, S, and Brush, GS. (2005). Mechanistic insight into the Cdc28-related protein kinase Ime2 through analysis of replication protein A phosphorylation. 4:1826-1833.

Campbell, PM, Singh, A, Williams, FJ, Frantz, K, Ulku, AS, Kelley, GG, and Der, CJ. (2006). Genetic and pharmacologic dissection of Ras effector utilization in oncogenesis. Methods Enzymol, in press.

Nishioka GM, Borikova AL, Sokolik CW. (2006). High resolution microprinting with an electrospray printer. FASEB Journal 20: A527-A527 Part 1 (conference poster presentation).

Goldstein, BG, Chao, HH, Yang, Y, Yermolina, YA, Tobias, JW, and Katz, JP. (2007). Overexpression of Kruppel-like factor 5 in esophageal epithelia in vivo leads to increased proliferation in basal but not suprabasal cells. American Journal of Physiology-Gastrointestinal and Liver Physiology. 292:G1784.

Klose, RJ, Gardner KE, Liang, G, Erdjument-Bromage, H, Tempst, P, and Zhang, Y. (2007). Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol. 27: 3951-3961.

Liang, G, Klose, RJ, Gardner, KE. and Zhang, Y. (2007). Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nat Struct Mol Biol. 14: 243-245.

Nun, TK, Kroll, DJ Oberlies, NH, Soejarto, DD, Case, RJ, Piskaut, P, Matainaho, T, Hilscher, C, Wang, L, Dittmer, DP, Gao, SJ, and Damania, B. (2007). Development of a fluorescence-based assay to screen antiviral drugs against Kaposi’s Sarcoma-associated Herpesvirus. Molecular Cancer Therapeutics. 6: 2360-2370.

Barrick CJ, Yu, M, Chao, HH, and Threadgill, DW. (2008).Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice. Toxicology and Applied Pharmacology. 228:315-325.

Hall, JR, Lee, HO, Bunker, BD, Dorn, ES, Rogers, GC, Duronio, RJ, and Cook JG. (2008). Cdt and Cdc6 are destabilized by rereplication-induced DNA damage. J Biol Chem. 283: 25356-25363.

Hacker KE, Lee CM, Rathmell WK. (2008) VHL type 2B mutations retain VBC complex form and function. PLoS One. 2008;3(11):e3801. doi: 10.1371/journal.pone.0003801. Epub 2008 Nov 25. PMID: 19030229

Bhatt, AP, Bhende, PM, Sin, SH, Roy, D, Dittmer, DP, and Damania, B. (2010). Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas. Blood, in press.

Stratford JK, Bentrem DJ, Anderson JM, Fan C, Volmar KA, Marron JS, Routh ED, Caskey LS, Samuel JC, Der CJ, Thorne LB, Calvo BF, Kim HJ, Talamonti MS, Iacobuzio-Donahue CA, Hollingsworth MA, Perou CM, Yeh JJ. (2010). A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma. PLoS Med. 2010 Jul 13;7(7):e1000307. doi: 10.1371/journal.pmed.1000307. PMID: 20644708

Hacker KE, Rathmell WK. (2010) Emerging molecular classification in renal cell carcinoma: implications for drug development. Target Oncol. 2010 Jun;5(2):75-84. doi: 10.1007/s11523-010-0144-7. Epub 2010 Jul 20. Review. PMID: 20645016

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